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To see an animation on PenJets® for lyophilized drugs. 


 

NEEDLE-FREE DELIVERY OF LYOPHILIZED DRUGS

PenJet® has patented technology that enables needle-free injections of multi-component drugs. These drugs can include both a pharmaceutical reagent and a diluent, which may be combined immediately prior to injection.

Multi-component drugs are frequently stored in separate vessels because they are not stable for long periods of time after being mixed. This makes it difficult to store them in either conventional, pre-filled syringes or needle-free injectors. PenJet’s® patented filling and mixing technology provides a safe and cost-effective solution to this problem, and is applicable to a host of pharmaceutical products.

PenJet® enables pharmaceutical manufacturers to package their innovative lyophilized drugs in a needle-free, single use, inexpensive jet injector. it is particularly relevant to the increasing number of highly potent, biotechnologically derived proteins that require lyophilization to maintain their required shelf life.

The patented devices include a variety of shuttle configurations that allow a reagent and a diluent to be contained in separate chambers and mixed immediately prior to injection. To give a needle-free injection with a PenJet® once the reagent and diluent are combined, a safety ring that avoids accidental triggering is removed, the nozzle is placed against a suitable injection site, such as the upper arm, thigh or stomach, and the PenJet® administers the injection when gently pressed. After use, the PenJet® can be safely discarded in any trash receptacle, or recycled into non-medical devices, since it has no needle and has injected all the medication or vaccine it contained.